USP nicotine refers to nicotine that meets the standards set by the United States Pharmacopeia (USP) for purity, quality, and consistency. The USP is a nonprofit organization that establishes standards for the identity, strength, quality, and purity of medicines, food ingredients, and dietary supplements. USP nicotine is typically used in pharmaceuticals, nicotine replacement therapies (NRTs), and other medicinal applications. It undergoes rigorous testing and analysis to ensure it meets specific criteria, including purity levels and absence of contaminants. Choosing USP-grade nicotine ensures a higher level of quality and safety in products intended for human consumption or medical use.